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Heinrich Heine University Düsseldorf (abbr. HHU; German: Heinrich-Heine-Universität Düsseldorf), named after German poet Heinrich Heine, is a public university in North Rhine-Westphalia, Germany, which was founded in 1965. It is the successor organization to Düsseldorf's Medical Academy of 1907.

Following several expansions throughout the decades, the university has comprised five faculties since 1993. Currently, more than 36,000 full-time students are studying at HHU and a total staff of approximately 3,600 people (academic and non-academic).